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Your doctor may also direct you to take vitamin b6 pyridoxine to help prevent certain side effects such as nerve problems from isoniazid.

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patients receiving midazolam should be monitored for signs of altered benzodiazepine response when isoniazid is initiated or discontinued.

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pyridoxine vitamin b 6 , deficiency is sometimes observed in adults with high doses of isoniazid and is considered probably due to its competition with pyridoxal phosphate for the enzyme apotryptophanase.
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The current four-medication regimen includes isoniazid nydrazid , rifampin rifadin ,.

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