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The patient in this case was secretly taking a number of contraindicated medications nortriptyline, bupropion, and a sympathomimetic drug for weight control as well as using double the amount of prescribed emsam two 12 mg patches at the same time.
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indicationsbupropion is an increase in mtdna mutations and clinical situations.
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this may reflect the negative media reports and the consequent reluctance of gps to prescribe bupropion.
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genotoxicity data indicate that bupropion is a weak bacterial mutagen, but not a mammalian mutagen, and therefore is of no concern as a human genotoxic agent.
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4 also, bupropion should not be taken by individuals undergoing abrupt cessation of alcohol or benzodiazepine use.
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The efficacy of bupropion hydrochloride extended-release tablets in the prevention of seasonal major depressive episodes was established in 3 placebo-controlled trials in adult outpatients with a history of mdd with an autumn-winter seasonal pattern as defined in the dsm see clinical studies .
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